All authors read and approved the final manuscript. When salivary gland tumors do arise in children, they preferentially affect major salivary glands, but minor salivary gland tumors have also been. Primary pulmonary pleomorphic adenoma is a very rare benign tumor that tends to arise in the large airways tumors tend to show small, branching, double layered ductules rather than ducts and less cartilaginous stroma as compared to. Transsphenoidal approach has become the surgery of choice for pituitary adenomas. A case report book pdf free download link or read online here in pdf. Controversies in the management of parotid tumors management of recurrent pleomorphic adenoma duration.
Pleomorphic adenoma is a benign neoplasm which is commonly encountered in the parotid gland and other major salivary glands. In this case report we are presenting a case of pleomorphic adenoma of hard palate in a 24 year old female patient who reported to our department with complaint of pain less swelling in the palatal region since one year. The commonest sites for intraoral pa are palate, buccal. This article presents a case of pleomorphic adenoma of the palatal minor salivary gland treated successfully by surgical excision. Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. You clearly have a thyroid problem, and this needs to be discussed in context of the bigger clinical picture. Approximately 10% of pleomorphic adenomas occur in the minor salivary glands with the palate being the most common site. Pleomorphic adenomas are benign and tend to increase in size slowly. Immunohistochemical pattern of pleomorphic adenoma. It involves the parotid of the major salivary glands and the palate of the minor salivary glands. In such cases, it is critical to make a definite diagnosis as each of these tumors has an entirely different treatment protocol.
View full size version of pleomorphic adenoma of the soft palate. Issue1 2015 swelling over hard palate for the last 10 months. Pleomorphic adenoma is the common salivary gland tumour encountered. The most common sites of the minor salivary glands are the palate, lips, cheeks, and throat. Doctor answers on symptoms, diagnosis, treatment, and more. Pleomorphic adenoma hard palate things you didnt know. It derives its name from the architectural pleomorphism variable. The purpose of this study was to collect observational data regarding age, size, symptoms, ct findings and treatment of pleomorphic adenoma of hard palate.
Pleomorphic adenoma, or benign mixed tumor, is the most common tumor of the parotid gland and represents 70% of all parotid neoplasms. Salivary gland tumors are rare in children and the incidence differs from the adult counterpart. The majority of minor salivary gland tumors are malignant. According to a study the most common site of pleomorphic adenoma of the minor salivary gland is the palate followed by lip, buccal mucosa, floor of mouth, tongue, tonsil, pharynx, retromolar area, and nasal cavity. Metastasizing pleomorphic adenoma occurred on average 16 years following the initial treatment of a benign pleomorphic adenoma. This case report discusses a case of intraoral salivary gland tumour in the hard palate. Imaging characteristics of recurrent pleomorphic adenoma.
Pleomorphic adenoma of hard palate international journal of community health and medical research vol. Salivary gland tumours constitute about less than 4 % of all head and neck tumours. We report 3 cases of pleomorphic adenoma of the minor salivary gland of the palate. Pleomorphic adenoma is the most common parotid gland tumor. Pleomorphic adenoma of the hard palate naseer mohammad,1 pavan kumar b,2 brahmaji rao j,3 yashwanth yadav4 abstract. Pleomorphic adenoma of minor salivary gland is most common in palate 10%, followed by lip 4%. Metastasizing pleomorphic salivary adenoma oncology.
The pleomorphic adenoma is the most common salivary gland tumor. Infrequently, it may arise from minor salivary glands and present as. It accounts for 7080% of all benign parotid tumors. Nevertheless, some complications can be occurred during surgical procedure. The palate is the most common site for minor gland mixed tumor. The aim of the article is to present a case of palatal pa, with a focus on the differential diagnosis and various aids of diagnosis and its successful treatment by surgical excision. Pleomorphic adenoma is a benign mixed tumour composed of various morphological patterns of epithelial and myoepithelial cells component, demarcated from surrounding tissues by fibrous capsule. Pleomorphic adenoma usually develops as a nontender nodular lesion with a slow growth rate persisting for years. Pleomorphic adenoma surgery recovery doctor answers.
The primary tumor arose most commonly from the parotid gland, followed by the minor salivary and submandibular glands. Pictures of pleomorphic adenoma benign mixed tumor of. Soft palate pleomorphic adenoma of a minor salivary gland. This distribution corresponds with that of psas in general. Surgical management of pleomorphic adenoma of parotid. Pleomorphic adenoma of palate a case report with ct and cbct features, 2014, 8, 8389. Pdf pleomorphic adenoma of the palate researchgate. She gave the history that the swelling had been there for 3 years, but grew quite rapidly in the past 3 months.
See them and ask what this means in your case and what should be done next. Intraoral examination revealed a soft tissue mass 1. A 60yearold male had a 3month history of a small soft palatal mass with progressing left cheek numbness, proptosis, and disturbed vision. Pleomorphic adenoma, is the most common tumor 50% of the major and minor salivary glands. Doctors give unbiased, helpful information on indications, contraindications, benefits, and complications. It progresses slowly and, left untreated, can produce signi. Pleomorphic adenoma is the most common benign tumor affecting the major salivary glands and infrequently arises from the minor salivary glands.
Most cases of palatal pleomorphic adenoma cause only a bulge in the palatal mucosa, but. Parotid gland happens to be the commonly involved one. Palatal pa presents clinically as a painless, slowgrowing mass found on posterior lateral aspect. Pleomorphic adenoma is the most common benign tumor affecting the major salivary glands and infrequently arises from the minor salivary.
Pleomorphic adenoma of the palate in a child and she denied drug allergy. Pleomorphic adenoma is the most common salivary gland tumor and accounts for approximately 80% of parotid tumors. Pleomorphic adenoma can be defined as a benign mixed tumor composed of epithelial and myoepithelial cells arranged with various morphological patterns, demarcated from surrounding tissues by fibrous capsule. Over 84% of pleomorphic adenomas occur in the parotid gland, 8% occur in the submandibular gland, and 6. There was no preceding history of trauma and no relevant past medical history. Carcinoma ex pleomorphic adenoma cxpa is an aggressive salivary gland malignancy and rare in minor salivary gland. International journal of research in health and allied. Histologically, it is characterized by the presence of cellular pleomorphism and is composed of an epithelial and connective tissue. Pleomorphic adenoma presenting a 2x2cm well circumscribed lesion on the palate of a 67year old female iarc screening group.
Pleomorphic adenoma may show various architectural and cytologic features that resemble other salivary tumors identifying areas typical of pleomorphic adenoma with triphasic ductal, myoepithelial and stromal components is helpful. A soft palate cxpa initially presenting as direct cavernous sinus cs invasion is very rare. Pleomorphic adenoma surgery, symptoms, causes, treatment. Pleomorphic adenoma is the most common amongst these, comprising 60 70% of all parotid tumours. About 8090 % of these tumours occur in the major salivary glands mainly parotid gland and 10 % of them occur in the minor salivary glands. Even though these tumours are painless and slow growing ones, it. Most of these tumours occur in major salivary glands. If you have had fna done, you have a doc following you.
It is found mostly in the parotid gland in middleaged women. The mass was surgically removed and confirmed to be a pleomorphic adenoma on histopathological analysis. Case studies were presented on pleomorphic adenoma of the palate in 2 male patients, aged 5 years and 16 years, providing strategies for diagnosing and treating pleomorphic adenoma of. Pleomorphic adenoma, palate, mixture of solid areas arrows and strands and nests of cells triangle in an area with edematous stroma. Salivary gland tumours are rare tumours, representing only about 3% of all. Kamala rawson, basavaraj n kallalli, kalpanagokul, ankur singh, pleomorphic adenoma of the palate. Pleomorphic adenoma of palate international journal of oral.
Seventy percent of the tumors of the minor salivary glands are pleomorphic adenomas, and the most common intraoral site is the palate, followed by the upper lip and buccal mucosa. It is commonly found in females than in males, with a malefemale ratio varying from 1. Pdf pleomorphic adenoma pa is the most common salivary gland tumor, accounting for about 4070% of all major and minor salivary gland tumors. The smaller the salivary gland that is affected, the more likely it is to trigger a malignant tumor. Pleomorphic adenoma is the commonest benign minor salivary gland tumor. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland. Pleomorphic adenoma of the palate pubmed central pmc. Carcinoma ex pleomorphic adenoma of soft palate with cavernous. Keywords palate, pleomorphic adenoma, surgical excision, surgical obturator abstract pleomorphic adenoma pa is the most common salivary gland tumor, accounting for about 4070% of all major and minor salivary gland tumors.
An external file that holds a picture, illustration, etc. Here we are presenting a case of giant pleomorphic adenoma of the parotid, being the largest in size to be excised in pakistan in. Pleomorphic adenoma pa is the most common salivary gland tumor, accounting for about 4070% of all major and minor salivary gland tumors. Pleomorphic adenoma is a benign neoplasm, which is commonly encountered in the parotid gland and other major salivary glands. A case report of 28 year old male patient diagnosed of pleomorphic adenoma of palate, is presented here. Removal of a massive pleomorphic adenoma on the palate using. Pdf pleomorphic adenoma is a benign tumor of the salivary glands that has elements of both epithelial and mesenchymal tissues. Pleomorphic adenoma is the most common benign salivary gland neoplasm. The hypothesis for recurrence of pleomorphic adenoma using this type of surgical approach is that microscopic portions of tumor perforate the capsule and are shared off resulting in a subtotal removal. Pleomorphic adenoma, also called benign mixed tumour, is the most common tumour of the salivary glands. At times they can also develop in minor salivary glands of the palate. Pleomorphic adenoma of minor salivary glands of hard palate is a rare benign tumour. Carcinoma ex pleomorphic adenoma of soft palate with.
Pleomorphic adenomas account for the majority of palatal tumours. Palatal pleomorphic adenoma is laterally located, rarely crossing the. Salivary gland tumors are rare and account for 23% of tumors occurring in the head and neck. Benign slow growing painless swelling since 3 years. It usually presents as slow growing submucosal mass on hard palate.
The commonest sites for intraoral pa are palate, buccal mucosa and lips. Pleomorphic adenoma is a mixed salivary gland tumor originating from the epithelial and mesodermal elements. A case report book pdf free download link book now. The palate being the most common site, followed by lip, buccal mucosa, floor of mouth, tongue, tonsil, pharynx. Pleomorphic adenoma an overview sciencedirect topics.
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